And now with no trace of the tumor, the family is thanking God.
According to Boston's Children Hospital, almost 300 children a year are diagnosed with DIPG.
Dr. Virginia Harrod of Dell Children's Medical Center said DIPG "is very rare, but when we see it, it is a devastating disease". The condition may cause vision loss, decreased ability to swallow, decreased ability to talk, and eventually difficulty breathing.
After diagnoses and a family-held benefit in August, the child was put through weeks of radiation.
"And we got it", an overjoyed Gena said.
"Praise God we did", said Scott. "The tumor is undetectable on the MRI scan, which is really unusual".
She clarified that she had no explanation for the change.
Today, 11-year-old Roxli Doss is a healthy kid.
Still, it's obvious the result it no fluke, since Roxli is back to her old self, and riding horses like she did before her illness.
Doctors acknowledge the tumor may return, but for now Roxli is just as active as she ever was.
The family tells KVUE they will continue to watch her closely and continue to undergo treatments as a precaution.
They prayed every day for her healing.
His wife added: "It's kind of our family thing that God healed Roxli".
Dr Harrold explained that Roxli's DIPG was confirmed by four different medical providers, including Johns Hopkins Medical Center, meaning the chances of her being mis-diagnosed were nearly impossible.