Other contributing factors to suicide - besides substance abuse and mental health disorders - detailed in the CDC's latest report included recent or impending crises, physical health problems, financial stress, losing housing and criminal or legal problems.
Twenty-five states had suicide-rate increases of more than 30 percent.
When the suicide rate is up 25 percent in America, it's clear that mental illness is a huge problem that too many people face alone. "The differences in the prevalence of life stressors was very small, so it is hard to attribute suicide to life stress per se".
Guns were the most common method used for suicide, accounting for nearly half of the people who died.
Firearms were found to be the most common method of suicide, again used by those both with and without mental health issues.
"Suicide in this country really is a problem that is impacted by so many factors". But suicide is such an unpredictable, often impulsive act that no single intervention has proved sufficient.
Suicide by stateThe study also broke down the data by state and found suicide rates varied widely.
"If you think of [suicide] as other leading causes of death, like AIDS and cancer, with the public health approach, mortality rates decline", Moutier said.
The study serves as a reminder, she says, that if someone in your life recently lost a job, ended a relationship, or is having some other life crisis, it's important to reach out. In Nevada, the only state that saw a decrease, the rate fell by 1 percent. During the study period, rate increases ranged from just under 6 percent in DE to over 57 percent in North Dakota.
The CDC is hoping future research delves into the specific causes of suicide trends, as NVDRS was capable of providing significant insight into decedent characteristics in more than half of the states.
The CDC researchers found that more than half of Americans who died by suicide had not been diagnosed with a mental health condition.
CDC Principal Deputy Director Dr. Anne Schuchat told NBC, "Middle-aged adults had the largest number of suicides and a particularly high increase in suicide rates".
In 2016, 745 suicides were reported in Minnesota. Historically, the suicide rate tracks with recessions, rising when times are bad and falling when they're better. "But these issues were [found] in all, with or without a mental health condition".
Glenn opened up on today's show, speaking from his own experiences with mental pain and describing the dangers that people face while going through depression.
And finally, Vermont has a lot of military veterans, and veterans as a group are twice as likely to die by suicide than the general population, Delaney said.
If you or someone you know may be considering suicide, call the 24-hour National Suicide Prevention Lifeline to talk anonymously with a counselor: 800-273-TALK (8255). It has to be paired with measures that would make suicidal people less likely to die even if they never went to see a doctor. If you suspect someone of needing immediate help, call 911.