Vincenzo Montella and his Sevilla players travel to Manchester United with a Champions League quarter-final place the prize if they can win on Tuesday.
Paul Pogba missed the win over Liverpool on Saturday with a minor leg injury but he was able to take part in training yesterday so could be in contention this evening.
Mourinho emphasised the need for his team to retain their dominance internationally after winning the Europa League last season.
United fans will be hoping that their side follow the example of Bayern Munich in 2015 when they drew 0-0 in the first leg of their last-16 clash with Shakhtar Donetsk.
Blind, Rojo and Herrera have made 13 Champions League appearances between them this season, but Jones is yet to appear in the competition. "So, of course, knockout becomes more important than league matches".
Manchester United go into Tuesday's game as favourites to qualify after their goal-less draw in the first leg, and they have their goalkeeper to thank for holding that advantage. "We don't know yet, but he trained a little bit after you left". I don't know if he will be fit for tomorrow yet.' Mourinho told the media during a press conference.
Rashford has scored three times in seven Champions League games this term, and he'll be aiming to add to that record if given the chance to do so against Sevilla.
De Boer - who lasted 77 days at Palace after losing four consecutive league games without his side scoring a goal - suggested after Rashford started his first game of 2018 against Liverpool, scoring twice, that he would be better off playing under another manager.