Conor McNamara: "The build-up to this game has been as much about watching the weather forecast as the team news". In the first five games under Paul Lambert, Stoke have improved allowing only four goals and picking up six points.
Stoke have captain Ryan Shawcross and striker Peter Crouch available again. "It's big-time football, and I can't praise the lads enough for their efforts".
Stoke could do the league double over Southampton for the first time in 50 years.
Southampton last won a Premier League game at home on November 26 - a run of eight without a victory - and they remain a point above the bottom three after being booed off at the end of both halves.
Stoke City have the bragging rights over Southampton over recent fixtures they have played each other; specifically at St. Mary's.
Manolo Gabbiadini ended a run of 16 games without a goal in all competitions for Southampton last time out - he has not scored in consecutive games for them since March 2017, when he scored in his first four appearances for the club.
The Potters have conceded a league-high 54 goals this season.
The Premier League match between Southampton and Stoke will be broadcast online.
They have the joint-worst away record, alongside West Brom, with seven points and only one victory.
Stoke defeated Southampton 2-1, with Mame Diouf and Peter Crouch scoring in the win. Offensively, Stoke have leaned heavily on Swiss winger Xherdan Shaqiri.