The Republican congresswoman hopes to come out on top in a crowded field of candidates to fill the seat being vacated by Sen.
"Like our president, I'm exhausted of PC politicians and their BS excuses", she says on the video.
McSally, who served 26 years in the USA military, also used her experience to hit out at the Democrats in the Senate in the video, saying, "after taking on terrorists in combat, the liberals in the Senate won't scare me one bit". She retired in 2010 as a full-bird colonel.
McSally is running off the platform that, right now, only she - and not her Republican rivals Kelli Ward and Joe Arpaio - are actually in office attempting to pass legislation. "Now, I am running for the Senate to fight the fights that must be won - on national security, economic security and border security". "She opposed Donald Trump as a candidate and has undermined him as president, which is why leading conservatives are rejecting McSally and are lining up behind a true reformer in Dr. Kelli Ward". The late former senator Barry Goldwater, R-Ariz., and Sen. John McCain in 2016.
Rep. Martha McSally released a 93-second ad on YouTube to kick off her Senate campaign this morning.
Earlier this week, she was seated near Trump at his hourlong public discussion with congressional Democrats and Republicans of immigration and border-security issues.
One thing is clear, a Republican can't win a primary without expressing support for Trump.
She was first elected to the House of Representatives in November 2014 and was re-elected two years later.
"As a member of the wildly unpopular Republican Congress, Mitch McConnell's handpicked candidate Rep. McSally has spent her career as a reliable vote for corporate special interests and Wall Street, not Arizona families", J.B. Poersch, the organization's president, said in a statement.
The GOP primary victor will likely face off against Rep. Kyrsten Sinema, the frontrunner in the Democratic primary.